SCHEMBL1016340

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1020475	0.88	HRH3 (0.37)	HRH3PARP1
	SCHEMBL1016565	0.82	PANK3 (0.41)	EGLN1PANK3HRH3DPP4IRAK4
	SCHEMBL1018089	0.75	HRH3 (0.39)	HRH3IRAK4PARP1
	SCHEMBL1018281	0.74	PARP1 (0.46)	HRH3PARP1
	SCHEMBL1014671	0.73	HRH3 (0.43)	EGLN1HRH3IRAK4
	SCHEMBL1019845	0.73	HRH3 (0.45)	HRH3USP14
	SCHEMBL1018602	0.72	HTT (0.38)	HRH3PARP1
	SCHEMBL1017081	0.72	HRH3 (0.41)	EGLN1HRH3IRAK4
	SCHEMBL1016401	0.72	HRH3 (0.41)	EGLN1HRH3DPP4DPP8DPP9
	SCHEMBL1016795	0.71	MEN1 (0.50)	HRH3IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.