SCHEMBL1016401

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1018271	0.81	HTT (0.41)	HRH3HTTNPSR1
	SCHEMBL1018143	0.78	HRH3 (0.45)	HRH3DPP4DPP8DPP9DPP7
	SCHEMBL1014671	0.78	HRH3 (0.43)	HRH3EGLN1KDM2BKCNH2
	SCHEMBL1019845	0.77	HRH3 (0.45)	HRH3USP14KCNH2MGLL
	SCHEMBL1016795	0.74	MEN1 (0.50)	HRH3DRD2DRD3MGLL
	SCHEMBL13006658	0.73	HRH3 (0.49)	HRH3DPP4KDM2B
	SCHEMBL1017157	0.72	KDM4E (0.42)	HRH3KCNH2
	SCHEMBL1016340	0.72	EGLN1 (0.40)	HRH3DPP4DPP8DPP9USP14
	SCHEMBL3770805	0.71	ALDH1A1 (0.52)	HRH3DPP4NPSR1
	SCHEMBL1017692	0.71	HRH3 (0.43)	HRH3KDM2BKCNH2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.