SCHEMBL10163843

SCHEMBL10163843

CC1CCC(c2ccc(-c3ccc(-c4ccc(C5CO5)c(F)c4F)cc3)cc2F)CC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.32
BRD4 O60885 1/20 0.31
ALOX5AP P20292 2/20 0.31
FEN1 P39748 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12999820 0.96 DGAT1 (0.31) DGAT1
SCHEMBL12999900 0.90 ALOX5AP (0.34) ALOX5APFEN1
SCHEMBL9015723 0.86 BRD4 (0.30) BRD4
SCHEMBL13000706 0.84 FASN (0.41)
SCHEMBL13111383 0.84 DGAT1 (0.36) DGAT1ALOX5APFEN1
SCHEMBL13262806 0.84 DGAT1 (0.35) DGAT1BRD4ALOX5APFEN1
SCHEMBL9019178 0.83
SCHEMBL10165408 0.82 OPRL1 (0.35) DGAT1
SCHEMBL10152928 0.82
SCHEMBL13262854 0.82 OPRL1 (0.35) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed