⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13136715 | 1.00 | — | — | |
| SCHEMBL3043575 | 0.78 | TSHR (0.34) | — | |
| SCHEMBL4970112 | 0.78 | TSHR (0.34) | — | |
| SCHEMBL28316767 | 0.74 | CTSS (0.41) | — | |
| SCHEMBL13741705 | 0.71 | — | — | |
| SCHEMBL3854088 | 0.71 | — | — | |
| SCHEMBL24724789 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL15413957 | 0.69 | CA1 (0.35) | — | |
| SCHEMBL21206997 | 0.67 | CA1 (0.39) | — | |
| SCHEMBL30471284 | 0.67 | EPHX1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021469-A1 | AMIDASES AND METHODS OF THEIR USE | CODEXIS, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120021469-A1 | AMIDASES AND METHODS OF THEIR USE | CODEXIS, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| US-7612215-B2 | Process for preparing 2-oxo-1-pyrrolidine derivatives by intramolecular allylation | UCB PHARMA, S.A. (BE) | 2009-11-03 | — | — | US | disclosed |
| US-7612215-B2 | Process for preparing 2-oxo-1-pyrrolidine derivatives by intramolecular allylation | UCB PHARMA, S.A. (BE) | 2009-11-03 | — | — | US | disclosed |
| US-20080125598-A1 | Process for Preparing 2-Oxo-1-Pyrrolidine Derivatives by Intramolecular Allylation | UCB, S.A. (BE) | 2008-05-29 | — | — | US | disclosed |
| US-20080125598-A1 | Process for Preparing 2-Oxo-1-Pyrrolidine Derivatives by Intramolecular Allylation | UCB, S.A. (BE) | 2008-05-29 | — | — | US | disclosed |