Sugi Predict

Sugi Predict / Compounds / SCHEMBL10165753

SCHEMBL10165753

SCHEMBL10165753

c1ccc(-n2c3ccccc3c3cc(-c4ccc(-c5ccc(-c6cccc7c6sc6ccccc67)cc5)cc4)ccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.49
▸ ATM Q13315 2/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ PRKDC P78527 5/20 0.38
▸ PARP14 Q460N5 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.35
▸ PIK3CD O00329 2/20 0.34
▸ PIK3CB P42338 2/20 0.34
▸ BRD4 O60885 1/20 0.34
▸ PIK3CA P42336 1/20 0.34
▸ MTOR P42345 1/20 0.34
▸ PIK3CG P48736 1/20 0.34
▸ KCNH2 Q12809 1/20 0.34
▸ BRDT Q58F21 1/20 0.34
▸ LIMK1 P53667 2/20 0.33
▸ TSPO P30536 1/20 0.33
▸ HDAC4 P56524 1/20 0.33
▸ PIM3 Q86V86 1/20 0.33
▸ TNKS O95271 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL896199 1.00 ALOX5 (0.49) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL15685664 0.99 ALOX5 (0.48) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL15685686 0.99 ALOX5 (0.48) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL20633640 0.98 ALOX5 (0.47) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL15685605 0.98 ALOX5 (0.47) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL18804958 0.98 ALOX5 (0.52) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL12088546 0.98 ALOX5 (0.49) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL10165760 0.97 ALOX5 (0.51) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL24173851 0.96 ALOX5 (0.48) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL24812231 0.96 ALOX5 (0.48) ALOX5ATMKDM4EL3MBTL1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 — — US disclosed
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 — — US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 — — US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element NUTF2, BRI3BP, CLINT1 ALOX5 1931/4885ATM 2465/4885KDM4E 2172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.