SCHEMBL10165775

SCHEMBL10165775

c1ccc(-n2c3ccc(-c4cccc(-c5cccc6c5oc5ccccc56)c4)cc3c3cc(-c4cccc(-c5cccc6c5oc5ccccc56)c4)ccc32)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.53
GGPS1 O95749 1/20 0.43
PRKDC P78527 9/20 0.43
PTGES2 Q9H7Z7 1/20 0.40
PLA2G2A P14555 3/20 0.40
PLA2G4A P47712 3/20 0.40
PLA2G10 O15496 1/20 0.40
ATM Q13315 2/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
ALDH1A1 P00352 1/20 0.36
PPARG P37231 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
NR2E3 Q9Y5X4 1/20 0.36
NCOR2 Q9Y618 1/20 0.36
PIK3CD O00329 2/20 0.34
PIK3CB P42338 2/20 0.34
PIK3CA P42336 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14979108 0.98 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL18804979 0.98 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL16634997 0.97 ALOX5 (0.53) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL15630328 0.97 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL457914 0.96 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL18020767 0.95 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL18020780 0.95 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL16648210 0.95 ALOX5 (0.53) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL18381749 0.95 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL18804982 0.94 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-9133173-B2 Carbazole compound, material for light-emitting element, organic semiconductor material, light-emitting element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120091887-A1 Carbazole Compound, Material for Light-Emitting Element, Organic Semiconductor Material, Light-Emitting Element NUTF2, BRI3BP, CLINT1 ALOX5 1931/4885GGPS1 2686/4885PRKDC 2968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.