Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2683659 | 0.91 | CTSS (1.00) | CTSS | |
| SCHEMBL2682347 | 0.91 | CTSS (1.00) | CTSS | |
| SCHEMBL2682257 | 0.91 | CTSS (1.00) | CTSS | |
| SCHEMBL2685202 | 0.91 | CTSS (1.00) | CTSS | |
| SCHEMBL2717163 | 0.91 | CTSS (1.00) | CTSS | |
| SCHEMBL2684379 | 0.90 | CTSS (1.00) | CTSS | |
| SCHEMBL2719308 | 0.90 | CTSS (1.00) | CTSS | |
| SCHEMBL2733075 | 0.90 | CTSS (1.00) | CTSS | |
| SCHEMBL2682259 | 0.90 | CTSS (0.88) | CTSS | |
| SCHEMBL2729463 | 0.89 | CTSS (1.00) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059507-A1 | PYRROLIDINE DERIVATIVES USED AS CATHEPSIN INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-05-10 | — | — | WO | disclosed |