Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRAT | O95237 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26205686 | 1.00 | LRAT (0.64) | LRATMEN1TRPV1HSD17B10TSHR | |
| SCHEMBL26205687 | 0.90 | TSHR (0.58) | LRATMEN1TRPV1HSD17B10TSHR | |
| SCHEMBL21454660 | 0.87 | LRAT (0.68) | LRATMEN1TRPV1HSD17B10TSHR | |
| SCHEMBL25733220 | 0.87 | LRAT (0.68) | LRATMEN1TRPV1HSD17B10TSHR | |
| SCHEMBL25733227 | 0.87 | LRAT (0.68) | LRATMEN1TRPV1HSD17B10TSHR | |
| SCHEMBL24804651 | 0.86 | LRAT (0.67) | LRATMEN1TRPV1HSD17B10TSHR | |
| SCHEMBL2736460 | 0.86 | LRAT (0.67) | LRATMEN1TRPV1HSD17B10TSHR | |
| SCHEMBL25733221 | 0.86 | LRAT (0.67) | LRATMEN1TRPV1HSD17B10TSHR | |
| SCHEMBL17480019 | 0.86 | HSD17B10 (0.55) | LRATMEN1TRPV1HSD17B10TSHR | |
| SCHEMBL12454820 | 0.86 | HSD17B10 (0.55) | LRATMEN1TRPV1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044503-A9 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2012-02-09 | — | — | WO | disclosed |
| WO-2011044538-A9 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011044503-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011044538-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2011-04-14 | — | — | WO | disclosed |