SCHEMBL12454820

SCHEMBL12454820

CC1OC(CO)C(OC2OC(CO)C(OC3OC(CO)C(O)C(O)C3N)C(O)C2N)C(O)C1N

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 1/20 0.55
▸ TSHR P16473 1/20 0.55
▸ MEN1 O00255 1/20 0.53
▸ LRAT O95237 1/20 0.53
▸ TRPV1 Q8NER1 1/20 0.53
▸ LMNA P02545 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ ALOX15 P16050 1/20 0.51
▸ BLM P54132 1/20 0.50
▸ RECQL P46063 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23640180 1.00 HSD17B10 (0.55) HSD17B10TSHRMEN1LRATTRPV1
SCHEMBL19074567 1.00 HSD17B10 (0.55) HSD17B10TSHRMEN1LRATTRPV1
SCHEMBL17879097 1.00 HSD17B10 (0.55) HSD17B10TSHRMEN1LRATTRPV1
SCHEMBL26471008 1.00 HSD17B10 (0.55) HSD17B10TSHRMEN1LRATTRPV1
SCHEMBL17480019 1.00 HSD17B10 (0.55) HSD17B10TSHRMEN1LRATTRPV1
SCHEMBL19337535 0.91 MEN1 (0.52) HSD17B10TSHRMEN1LRATTRPV1
SCHEMBL12859458 0.91 MEN1 (0.52) HSD17B10TSHRMEN1LRATTRPV1
SCHEMBL20067007 0.90 MEN1 (0.46) HSD17B10TSHRMEN1LRATTRPV1
SCHEMBL13821014 0.90 MEN1 (0.46) HSD17B10TSHRMEN1LRATTRPV1
SCHEMBL26170073 0.90 MEN1 (0.46) HSD17B10TSHRMEN1LRATTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8916693-B2 Monoconjugated chitosans as delivery agents for small interfering nucleic acids NEKTAR THERAPEUTICS (US) 2014-12-23 — — US disclosed
US-20120238735-A1 Monoconjugated Chitosans as Delivery Agents for Small Interfering Nucleic Acids NEKTAR THERAPEUTICS (CA) 2012-09-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238735-A1 Monoconjugated Chitosans as Delivery Agents for Small Interfering Nucleic Acids CHIA, CLTA, CLTC HSD17B10 4413/4885TSHR 3886/4885MEN1 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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