Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2671871 | 1.00 | CYP2C9 (0.42) | CYP2C9ADORA2AADORA2BADORA1POLB | |
| SCHEMBL4135131 | 0.84 | CYP2C9 (0.40) | CYP2C9POLBNPSR1NPC1RAB9A | |
| SCHEMBL17859724 | 0.84 | CYP2C9 (0.40) | CYP2C9ADORA2AADORA2BADORA1POLB | |
| SCHEMBL27679283 | 0.84 | CYP2C9 (0.40) | CYP2C9ADORA2AADORA2BADORA1POLB | |
| SCHEMBL10136090 | 0.83 | ADORA2A (0.40) | CYP2C9ADORA2AADORA2BADORA1POLB | |
| SCHEMBL4072774 | 0.83 | ADORA2A (0.40) | CYP2C9ADORA2AADORA2BADORA1POLB | |
| SCHEMBL1324360 | 0.82 | CYP2C9 (0.41) | CYP2C9POLBNPSR1NPC1RAB9A | |
| SCHEMBL11269373 | 0.82 | CYP2C9 (0.62) | CYP2C9POLBNPSR1NPC1RAB9A | |
| SCHEMBL4181528 | 0.82 | CYP2C9 (0.41) | CYP2C9POLBNPSR1NPC1RAB9A | |
| SCHEMBL167038 | 0.82 | CYP2C9 (0.62) | CYP2C9POLBNPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170101384-A1 | ANDROGEN RECEPTOR ANTAGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-04-13 | — | — | US | disclosed |
| US-20120165437-A1 | AQUEOUS PIGMENT DISPERSION AND AQUEOUS INK FOR INKJET RECORDING | FUJIFILM CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101384-A1 | ANDROGEN RECEPTOR ANTAGONISTS | AR, LHCGR, FSHR | CYP2C9 1497/4885ADORA2A 110/4885ADORA2B 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.