Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13811311 | 1.00 | ALDH1A1 (0.32) | ALDH1A1LMNAPOLBTXNRD1 | |
| SCHEMBL13912283 | 0.83 | ALDH1A1 (0.35) | ALDH1A1LMNAPOLBTXNRD1 | |
| SCHEMBL13869136 | 0.76 | FUCA1 (0.35) | ALDH1A1LMNAPOLB | |
| SCHEMBL2638533 | 0.70 | — | — | |
| SCHEMBL14962551 | 0.70 | — | — | |
| SCHEMBL13293233 | 0.70 | — | — | |
| SCHEMBL13287807 | 0.70 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL13185878 | 0.69 | — | — | |
| SCHEMBL13446652 | 0.69 | — | — | |
| SCHEMBL17196343 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8206914-B2 | Evolving new molecular function | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-06-26 | — | — | US | disclosed |
| US-20110190141-A1 | Evolving New Molecular Function | PRESIDENT AND FELLOWS OF HAVARD COLLEGE (US) | 2011-08-04 | — | — | US | disclosed |
| US-7771935-B2 | Evolving new molecular function | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-08-10 | — | — | US | disclosed |
| US-7557068-B2 | Evolving new molecular function | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-07-07 | — | — | US | disclosed |
| US-7491494-B2 | Evolving new molecular function | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-02-17 | — | — | US | disclosed |