Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 5/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.34 |
| ▸ | ITGAL | P20701 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18868586 | 0.88 | ITGB2 (0.39) | PNMTITGB2ICAM1ITGALHTR2B | |
| SCHEMBL10129638 | 0.80 | PNMT (0.42) | PNMTHDAC6HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL23422078 | 0.79 | PNMT (0.41) | PNMTHDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL29183920 | 0.77 | ADORA1 (0.49) | LMNAPNMT | |
| SCHEMBL28978402 | 0.76 | PNMT (0.45) | PNMTHTR2AHTR2CHTR2B | |
| SCHEMBL15445349 | 0.76 | PNMT (0.45) | PNMTHTR2AHTR2CHTR2B | |
| SCHEMBL10129610 | 0.76 | ITGAL (0.56) | ITGB2ICAM1ITGAL | |
| SCHEMBL12749585 | 0.75 | ITGB2 (0.37) | ITGB2ICAM1ITGAL | |
| Hydrochloric Acid SCHEMBL29547703 | 0.75 | ITGB2 (0.55) | ITGB2ICAM1ITGAL | |
| SCHEMBL21413286 | 0.75 | PNMT (0.46) | PNMTHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682537-B1 | MODULATORS OF CELLULAR ADHESION | SARCODE BIOSCIENCE INC (US) | 2012-03-28 | — | — | EP | disclosed |