Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP12 | P39900 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655095 | 0.93 | TSHR (0.62) | TSHRHPGDMAPTALDH1A1TP53 | |
| SCHEMBL28029409 | 0.90 | TSHR (0.51) | TSHRHPGDMAPTALDH1A1CYP3A4 | |
| SCHEMBL27865301 | 0.86 | EGLN1 (0.45) | TSHRMAPTALDH1A1CYP3A4KDM6B | |
| SCHEMBL19845038 | 0.84 | TSHR (0.45) | TSHRHPGDMAPTALDH1A1TP53 | |
| SCHEMBL19845035 | 0.84 | TSHR (0.47) | TSHRHPGDMAPTALDH1A1TP53 | |
| SCHEMBL8965855 | 0.84 | TSHR (0.75) | TSHRHPGDALDH1A1TP53HIF1A | |
| Succinic Acid SCHEMBL28756647 | 0.82 | TSHR (0.62) | TSHRHPGDMAPTALDH1A1TP53 | |
| SCHEMBL19845084 | 0.82 | TSHR (0.49) | TSHRHPGDMAPTALDH1A1TP53 | |
| SCHEMBL19845081 | 0.82 | TSHR (0.49) | TSHRHPGDMAPTALDH1A1TP53 | |
| SCHEMBL1071857 | 0.82 | TSHR (0.49) | TSHRHPGDMAPTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037819-A1 | OPTICAL ISOMER | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2018-02-08 | — | — | US | disclosed |
| US-8529803-B2 | Curable coloring composition, color filter and method for producing same, and quinophthalone dye | FUJIFILM CORPORATION (JP) | 2013-09-10 | — | — | US | disclosed |
| US-20120112142-A1 | CURABLE COLORING COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING SAME, AND QUINOPHTHALONE DYE | FUJIFILM CORPORATION (JP) | 2012-05-10 | — | — | US | disclosed |