SCHEMBL1016884

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1018319	0.98	MLNR (0.48)	MLNRALDH1A1TSHRKMT2AMTNR1B
	SCHEMBL1017918	0.97	MLNR (0.47)	MLNRALDH1A1TSHRKMT2AMTNR1B
	SCHEMBL1018056	0.94	ALDH1A1 (0.42)	MLNRALDH1A1TSHRKMT2AMTNR1B
	SCHEMBL1014260	0.93	ALDH1A1 (0.45)	MLNRALDH1A1TSHRKMT2AKDM4E
	SCHEMBL1016571	0.92	ALDH1A1 (0.46)	MLNRALDH1A1TSHRKMT2AKDM4E
	SCHEMBL1017111	0.91	MAPT (0.42)	ALDH1A1TSHRKMT2AMTNR1BKDM4E
	SCHEMBL1017983	0.89	ALDH1A1 (0.42)	ALDH1A1TSHRKMT2AKDM4EHTT
	SCHEMBL1017014	0.88	ALDH1A1 (0.41)	MLNRALDH1A1TSHRKMT2AKDM4E
	SCHEMBL1016311	0.88	ALDH1A1 (0.43)	ALDH1A1TSHRKMT2AKDM4EHTT
	SCHEMBL1015085	0.87	ALDH1A1 (0.47)	ALDH1A1TSHRKMT2AKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.