SCHEMBL10168994

SCHEMBL10168994

Cc1nc(NCc2ccccc2)nc(Nc2cc(S(=O)(=O)O)cc3cc(S(=O)(=O)O)ccc23)n1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
KCNH3 Q9ULD8 1/20 0.40
GBA1 P04062 1/20 0.40
CASP6 P55212 1/20 0.40
SCN9A Q15858 1/20 0.39
CRHR1 P34998 1/20 0.39
RHOA P61586 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10168998 0.87 GBA1 (0.41) HTTSMN1; SMN2PTGS1PTGS2KCNH3
SCHEMBL10169005 0.81 KCNH3 (0.57) GAAKCNH3
SCHEMBL10168983 0.80 PDE5A (0.53) GAAHTTSMN1; SMN2NPSR1KCNH3
SCHEMBL10168989 0.76 PDE5A (0.46) GAAKCNH3CRHR1
SCHEMBL10174707 0.75 PTK2 (0.40) CASP6RHOA
SCHEMBL1754808 0.74 GBA1 (0.43) KCNH3GBA1
SCHEMBL10168979 0.74 CA9 (0.55) KCNH3
SCHEMBL15488931 0.74 CA1 (0.47) GAASMN1; SMN2NPSR1KCNH3GBA1
SCHEMBL10411694 0.73 CA12 (0.44) CASP6RHOA
SCHEMBL1754814 0.72 GBA1 (0.43) GAAKCNH3GBA1CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8657433-B2 Porphyrazine coloring matter, ink composition, recording method, and colored object NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-02-25 US disclosed
US-20120081457-A1 PORPHYRAZINE COLORING MATTER, INK COMPOSITION, RECORDING METHOD, AND COLORED OBJECT NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-04-05 US disclosed