Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.68 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.48 |
| ▸ | TUBB | P07437 | 4/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.48 |
| ▸ | BCR | P11274 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258014 | 0.91 | SRC (0.71) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10084848 | 0.89 | SRC (0.80) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL254944 | 0.89 | SRC (0.68) | SRCCHRM3TUBB4ATUBBTUBA3C | |
| SCHEMBL255157 | 0.82 | SRC (1.00) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19291803 | 0.81 | SRC (0.69) | SRCCHRM3TUBB4ATUBBTUBA3C | |
| SCHEMBL12301410 | 0.80 | SRC (0.59) | SRCCHRM3TUBB4ATUBBTUBA3C | |
| SCHEMBL254904 | 0.80 | SRC (0.69) | SRCCHRM3TUBB4ATUBBTUBA3C | |
| SCHEMBL10084852 | 0.80 | SRC (0.84) | SRCCHRM3TUBB4ATUBBTUBA3C | |
| SCHEMBL13553566 | 0.79 | CHRM3 (0.55) | SRCCHRM3SIGMAR1 | |
| Kx2-361 SCHEMBL254057 | 0.79 | SRC (1.00) | SRCTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836169-B9 | COMPOSITIONS AND METHODS OF TREATING CELL PROLIFERATION DISORDERS | KINEX PHARMACEUTICALS LLC (US) | 2012-07-04 | — | — | EP | disclosed |
| EP-1836169-B1 | COMPOSITIONS AND METHODS OF TREATING CELL PROLIFERATION DISORDERS | KINEX PHARMACEUTICALS LLC (US) | 2012-02-08 | — | — | EP | disclosed |