Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 1.00 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.58 |
| ▸ | TUBB | P07437 | 5/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | LYN | P07948 | 1/20 | 0.58 |
| ▸ | BCR | P11274 | 1/20 | 0.58 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Kx2-361 SCHEMBL29385376 | 1.00 | SRC (1.00) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11917539 | 0.92 | SRC (0.85) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10084852 | 0.91 | SRC (0.84) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19867220 | 0.90 | SRC (0.82) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11917548 | 0.90 | SRC (0.82) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23761959 | 0.90 | SRC (0.82) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20286612 | 0.90 | SRC (0.81) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL254399 | 0.90 | SRC (0.81) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12158487 | 0.90 | SRC (0.81) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11917549 | 0.90 | SRC (0.81) | SRCTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| CN-115477608-B | Tubulin inhibitor and preparation method and application thereof | 成都贝诺科成生物科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-114516832-B | Tubulin inhibitor and preparation method and application thereof | 成都贝诺科成生物科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| US-20230167060-A1 | COMPOSITION AND METHODS FOR MODULATING A KINASE CASCADE | ATHENEX, INC. | 2023-06-01 | — | — | US | disclosed |
| US-20230167060-A1 | COMPOSITION AND METHODS FOR MODULATING A KINASE CASCADE | ATHENEX, INC. | 2023-06-01 | — | — | US | disclosed |
| US-20230167060-A1 | COMPOSITION AND METHODS FOR MODULATING A KINASE CASCADE | ATHENEX, INC. | 2023-06-01 | — | — | US | disclosed |
| CN-115477608-A | Tubulin inhibitor and preparation method and application thereof | 成都贝诺科成生物科技有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-114516832-A | Tubulin inhibitor and preparation method and application thereof | 成都贝诺科成生物科技有限公司 | 2022-05-20 | — | — | CN | disclosed |
| US-11325885-B2 | Method for treating stomach cancer | KING ABDULAZIZ UNIVERSITY (SA) | 2022-05-10 | — | — | US | disclosed |
| US-20100249130-A1 | BIARYL COMPOSITIONS AND METHODS FOR MODULATING A KINASE CASCADE | KINEX PHARMACEUTICALS, LLC (US) | 2010-09-30 | — | — | US | disclosed |
| WO-2008127728-A1 | BIARYL COMPOSITIONS AND METHODS FOR MODULATING A KINASE CASCADE | KINEX PHARMACEUTICALS, LLC (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008002676-A9 | BIARYL COMPOSITIONS AND METHODS FOR MODULATING A KINASE CASCADE | KINEX PHARMACEUTICALS LLC (US) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008002676-A2 | BIARYL COMPOSITIONS AND METHODS FOR MODULATING A KINASE CASCADE | KINEX PHARMACEUTICALS, LLC (US) | 2008-01-03 | — | — | WO | disclosed |
| US-7300931-B2 | Compositions for treating cell proliferation disorders | KINEX PHARMACEUTICALS, LLC (US) | 2007-11-27 | — | — | US | disclosed |
| US-7300931-B2 | Compositions for treating cell proliferation disorders | KINEX PHARMACEUTICALS, LLC (US) | 2007-11-27 | — | — | US | disclosed |
| US-20070197783-A1 | Compositions and methods of treating cell proliferation disorders | SAGARD HEALTHCARE ROYALTY PARTNERS, LP, AS ADMINISTRATIVE AGENT (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197783-A1 | Compositions and methods of treating cell proliferation disorders | SAGARD HEALTHCARE ROYALTY PARTNERS, LP, AS ADMINISTRATIVE AGENT (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070015752-A1 | Biaryl compositions and methods for modulating a kinase cascade | SAGARD HEALTHCARE ROYALTY PARTNERS, LP, AS ADMINISTRATIVE AGENT (CA) | 2007-01-18 | — | — | US | disclosed |
| US-20070015752-A1 | Biaryl compositions and methods for modulating a kinase cascade | SAGARD HEALTHCARE ROYALTY PARTNERS, LP, AS ADMINISTRATIVE AGENT (CA) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015752-A1 | Biaryl compositions and methods for modulating a kinase cascade | MAP3K3, MAP3K2, MAP3K20 | SRC 76/4885TUBB4A 2391/4885TUBB 2092/4885 |
| US-20230167060-A1 | COMPOSITION AND METHODS FOR MODULATING A KINASE CASCADE | MAP3K1, MAP3K6, MAP3K11 | SRC 96/4885TUBB4A 3755/4885TUBB 3519/4885 |
| US-11325885-B2 | Method for treating stomach cancer | TUBB, TUBB1, TUBA1C | SRC 5/4885TUBB4A 9/4885TUBB 1/4885 |
| US-20070197783-A1 | Compositions and methods of treating cell proliferation disorders | MKI67, CCNC, CCNA1 | SRC 430/4885TUBB4A 218/4885TUBB 342/4885 |
| US-20100249130-A1 | BIARYL COMPOSITIONS AND METHODS FOR MODULATING A KINASE CASCADE | MAP3K2, MAP3K3, MAP3K6 | SRC 112/4885TUBB4A 1470/4885TUBB 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.