SCHEMBL10169748

SCHEMBL10169748

CCC(C)C(=O)Nc1ccc(S(=O)(=O)N(C)C)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.69
CA2 P00918 5/20 0.69
CA7 P43166 5/20 0.69
CA14 Q9ULX7 5/20 0.69
SMN1; SMN2 Q16637 3/20 0.59
ALDH1A1 P00352 4/20 0.52
HPGD P15428 1/20 0.52
MAPT P10636 1/20 0.51
HSD17B10 Q99714 1/20 0.51
PKM P14618 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
GAA P10253 1/20 0.50
ABCC9 O60706 1/20 0.50
ABCC8 Q09428 1/20 0.50
KCNJ11 Q14654 1/20 0.50
KCNJ8 Q15842 1/20 0.50
NAMPT P43490 1/20 0.49
NPC1 O15118 1/20 0.49
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13566682 0.83 CA1 (0.75) CA1CA2CA7CA14
SCHEMBL9923561 0.82 CA1 (1.00) CA1CA2CA7CA14PKM
SCHEMBL16615791 0.80 ALDH1A1 (0.65) SMN1; SMN2ALDH1A1MAPTPKMMEN1
SCHEMBL6361275 0.79 CA1 (0.69) CA1CA2CA7CA14HSD17B10
SCHEMBL19592334 0.78 CA1 (0.59) CA1CA2CA7CA14SMN1; SMN2
SCHEMBL14199191 0.78 CA1 (0.68) CA1CA2CA7CA14
SCHEMBL1104218 0.77 CA1 (0.66) CA1CA2CA7CA14SMN1; SMN2
SCHEMBL24243431 0.77 CA1 (0.57) CA1CA2CA7CA14SMN1; SMN2
SCHEMBL12125174 0.76 CA1 (0.64) CA1CA2CA7CA14ALDH1A1
SCHEMBL7570377 0.76 GAA (0.69) CA1CA2SMN1; SMN2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed