Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148011 | 0.93 | P2RX7 (0.53) | P2RX7IL1B | |
| SCHEMBL10169773 | 0.93 | P2RX7 (0.47) | P2RX7IL1B | |
| SCHEMBL8132875 | 0.88 | P2RX7 (0.52) | P2RX7IL1B | |
| SCHEMBL8123607 | 0.86 | P2RX7 (0.54) | P2RX7IL1B | |
| SCHEMBL8139257 | 0.86 | P2RX7 (0.54) | P2RX7IL1B | |
| SCHEMBL8140671 | 0.84 | P2RX7 (0.43) | P2RX7 | |
| SCHEMBL10169767 | 0.83 | P2RX7 (0.40) | P2RX7 | |
| SCHEMBL8132877 | 0.81 | P2RX7 (0.52) | P2RX7IL1B | |
| SCHEMBL10169765 | 0.80 | P2RX7 (0.40) | P2RX7IL1B | |
| SCHEMBL305529 | 0.80 | P2RX7 (0.54) | P2RX7IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093265-B2 | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof | RENOVIS, INC. (US) | 2012-01-10 | — | — | US | disclosed |