Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 4/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382142 | 0.80 | CA12 (0.55) | MAOBMAOACA12CA9POLB | |
| SCHEMBL282766 | 0.77 | CA12 (0.49) | MAOBMAOACA12CA9POLB | |
| SCHEMBL19187891 | 0.76 | CA12 (0.41) | MAOACA12CA9CA1CA2 | |
| SCHEMBL9826458 | 0.74 | HDAC3 (0.52) | MAOBMAOASMN1; SMN2MAPTLMNA | |
| SCHEMBL8178252 | 0.73 | CA12 (0.51) | MAOBMAOACA12CA9POLB | |
| SCHEMBL28155728 | 0.73 | MAOB (0.49) | MAOBMAOACA12CA9POLB | |
| SCHEMBL5711170 | 0.73 | CA12 (0.54) | MAOBMAOACA12CA9POLB | |
| Hydrochloric Acid SCHEMBL7803213 | 0.72 | MAOB (0.48) | MAOBMAOACA12CA9POLB | |
| SCHEMBL8618928 | 0.71 | CA12 (0.55) | MAOBMAOACA12CA9POLB | |
| SCHEMBL27818145 | 0.71 | CA12 (0.43) | MAOBMAOACA12CA9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032545-A1 | PROCESSES FOR PREPARING DRONEDARONE AND ITS INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |