Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.46 |
| ▸ | TNNC1 | P63316 | 6/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.46 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566429 | 0.89 | S1PR1 (0.60) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| Hydrochloric Acid SCHEMBL567052 | 0.89 | S1PR1 (0.59) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| SCHEMBL8495816 | 0.76 | S1PR1 (0.73) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| SCHEMBL12337241 | 0.76 | S1PR1 (0.73) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| SCHEMBL8535469 | 0.75 | S1PR1 (0.71) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| SCHEMBL2013316 | 0.75 | S1PR1 (0.71) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| Hydrochloric Acid SCHEMBL2462141 | 0.75 | S1PR1 (0.71) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| SCHEMBL10139273 | 0.74 | S1PR1 (0.43) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| SCHEMBL2468253 | 0.73 | S1PR1 (1.00) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| Amiselimod SCHEMBL2463680 | 0.73 | S1PR1 (1.00) | S1PR1S1PR3TNNC1S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120034270-A1 | S1P Receptors Modulators | AKAAL PHARMA PTY LTD (AU) | 2012-02-09 | — | — | US | disclosed |
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034270-A1 | S1P Receptors Modulators | S1PR1, S1PR5, S1PR3 | S1PR1 1/4885S1PR3 3/4885TNNC1 4849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.