Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | POLRMT | O00411 | 1/20 | 0.36 |
| ▸ | BTN3A1 | O00481 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881567 | 1.00 | CYP3A4 (0.41) | CYP3A4CYP2C9POLRMTBTN3A1 | |
| SCHEMBL21283660 | 0.94 | CYP3A4 (0.42) | CYP3A4CYP2C9POLRMTBTN3A1 | |
| SCHEMBL21284203 | 0.92 | CYP3A4 (0.42) | CYP3A4CYP2C9POLRMTBTN3A1 | |
| SCHEMBL881565 | 0.89 | POLRMT (0.35) | CYP3A4CYP2C9POLRMT | |
| SCHEMBL18214641 | 0.89 | POLRMT (0.35) | CYP3A4CYP2C9POLRMT | |
| SCHEMBL26288028 | 0.89 | CYP3A4 (0.42) | CYP3A4CYP2C9POLRMTBTN3A1 | |
| SCHEMBL26288030 | 0.89 | CYP3A4 (0.42) | CYP3A4CYP2C9POLRMTBTN3A1 | |
| SCHEMBL24120253 | 0.88 | CYP3A4 (0.40) | CYP3A4CYP2C9POLRMTBTN3A1 | |
| SCHEMBL24088384 | 0.88 | CYP3A4 (0.40) | CYP3A4CYP2C9POLRMTBTN3A1 | |
| SCHEMBL25804205 | 0.88 | CYP3A4 (0.40) | CYP3A4CYP2C9POLRMTBTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150608-B1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES INC (US) | 2019-04-10 | — | — | EP | disclosed |
| EP-3150608-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | Gilead Sciences, Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| WO-2012039787-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |