Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | RGS12 | O14924 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.61 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2993181 | 0.86 | EGFR (0.62) | EGFRMAPTRGS12ALDH1A1LCK | |
| SCHEMBL1705430 | 0.84 | EGFR (0.75) | EGFRMAPTRGS12ALDH1A1LCK | |
| SCHEMBL9163440 | 0.84 | EGFR (1.00) | EGFRMAPTRGS12ALDH1A1LCK | |
| SCHEMBL9252849 | 0.80 | EGFR (0.72) | EGFRMAPTRGS12ALDH1A1LCK | |
| SCHEMBL11510755 | 0.79 | EGFR (0.71) | EGFRMAPTRGS12ALDH1A1LCK | |
| SCHEMBL2989135 | 0.78 | EGFR (0.80) | EGFRMAPTRGS12ALDH1A1LCK | |
| SCHEMBL11981619 | 0.77 | EGFR (0.79) | EGFRMAPTRGS12ALDH1A1LCK | |
| Hydrochloric Acid SCHEMBL2992201 | 0.77 | EGFR (0.77) | EGFRMAPTRGS12ALDH1A1LCK | |
| SCHEMBL7158986 | 0.76 | MAPT (0.66) | EGFRMAPTRGS12ALDH1A1LCK | |
| SCHEMBL412644 | 0.76 | HKDC1 (0.74) | EGFRMAPTRGS12ALDH1A1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021519-A1 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) | 2012-01-26 | — | — | US | disclosed |