SCHEMBL1017330

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12490852	0.80	HTR2C (0.78)	HTR2CPOLBSMN1; SMN2TNKS2CYP3A4
	SCHEMBL2793592	0.80	CDK2 (0.48)	CDK4CCND3
	Hydrochloric Acid SCHEMBL6298979	0.79	HTR2C (0.76)	HTR2CPOLBSMN1; SMN2TNKS2CYP3A4
	Trifluoroacetic Acid SCHEMBL19664864	0.79	HTR2C (0.62)	HTR2CPOLBSMN1; SMN2TNKS2CYP3A4
	SCHEMBL16836140	0.78	HTR2C (0.55)	HTR2CPOLBSMN1; SMN2TNKS2CYP3A4
	SCHEMBL3830137	0.78	HTR2C (0.51)	HTR2CPOLBSMN1; SMN2TNKS2CYP3A4
	SCHEMBL18549884	0.77	HTR2C (0.50)	HTR2CPOLBSMN1; SMN2TNKS2CYP3A4
	SCHEMBL12953054	0.75	CYP2C9 (0.40)	XDHTNKS2WNT1GSK3BDYRK1A
	SCHEMBL18550356	0.75	HTR2C (0.53)	HTR2CPOLBSMN1; SMN2TNKS2PNMT
	SCHEMBL28745314	0.75	HTR2C (0.48)	HTR2CPOLBSMN1; SMN2TNKS2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.