Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.62 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12490852 | 0.88 | HTR2C (0.78) | HTR2CTNKS2CYP3A4HTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL6298979 | 0.87 | HTR2C (0.76) | HTR2CTNKS2CYP3A4HTR2AHTR2B | |
| Trifluoroacetic Acid SCHEMBL17893733 | 0.86 | HTR2C (0.45) | HTR2CPOLBSMN1; SMN2NTRK1 | |
| Trifluoroacetic Acid SCHEMBL18550341 | 0.80 | HTR2C (0.41) | HTR2CCYP3A4HTR2AHTR2BPOLB | |
| Trifluoroacetic Acid SCHEMBL18550031 | 0.79 | HTR2C (0.38) | HTR2CCYP3A4HTR2BPOLBSMN1; SMN2 | |
| SCHEMBL1017330 | 0.79 | HTR2C (0.52) | HTR2CTNKS2CYP3A4HTR2AHTR2B | |
| SCHEMBL21042223 | 0.77 | HTR2C (1.00) | HTR2CTNKS2CYP3A4HTR2AHTR2B | |
| Trifluoroacetic Acid SCHEMBL29608658 | 0.77 | ENPP2 (0.53) | HTR2C | |
| SCHEMBL19711852 | 0.77 | HTR2C (0.50) | HTR2CTNKS2CYP3A4HTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL30613766 | 0.76 | HTR2C (0.97) | HTR2CTNKS2CYP3A4HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227362-B2 | Anti-pulmonary tuberculosis nitroimidazole derivative | MEDSHINE DISCOVERY INC. (CN) | 2019-03-12 | — | — | US | disclosed |
| US-20180162878-A1 | ANTI-PULMONARY TUBERCULOSIS NITROIMIDAZOLE DERIVATIVE | MEDSHINE DISCOVERY INC. (CN) | 2018-06-14 | — | — | US | disclosed |
| EP-3252059-A1 | ANTI-PULMONARY TUBERCULOSIS NITROIMIDAZOLE DERIVATIVE | Medshine Discovery Inc. (CN) | 2017-12-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162878-A1 | ANTI-PULMONARY TUBERCULOSIS NITROIMIDAZOLE DERIVATIVE | NDUFV1, NDUFV2, MT-ND4 | HTR2C 4132/4885TNKS2 1074/4885CYP3A4 844/4885 |
| US-10227362-B2 | Anti-pulmonary tuberculosis nitroimidazole derivative | NDUFV1, NDUFV2, MT-ND4 | HTR2C 4132/4885TNKS2 1074/4885CYP3A4 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.