Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263353 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDPOLBALOX12 | |
| SCHEMBL1399350 | 0.82 | KCNA5 (0.44) | KCNA5POLBKDM4AKMT2ALMNA | |
| SCHEMBL4477248 | 0.81 | KCNA5 (0.49) | KCNA5ALDH1A1HPGDPOLBKDM4A | |
| SCHEMBL7363894 | 0.81 | KCNA5 (0.45) | KCNA5POLBKDM4AKMT2ALMNA | |
| SCHEMBL8018113 | 0.79 | KCNA5 (0.56) | KCNA5POLBKDM4AKMT2ALMNA | |
| SCHEMBL30159605 | 0.79 | KCNA5 (0.56) | KCNA5POLBKDM4AKMT2ALMNA | |
| SCHEMBL2061998 | 0.76 | KCNA5 (0.54) | KCNA5ALDH1A1HPGDPOLBKDM4A | |
| SCHEMBL3417084 | 0.74 | HPGD (0.60) | ALDH1A1HPGDKMT2AGAA | |
| SCHEMBL6874894 | 0.74 | KCNA5 (0.52) | KCNA5POLBTDP1KDM4AKMT2A | |
| SCHEMBL5792738 | 0.74 | KCNA5 (0.52) | KCNA5HSD17B10POLBKDM4ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271624-A1 | IMINOPYRIDINE DERIVATIVES AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2011-01-12 | — | — | EP | disclosed |