SCHEMBL1017368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1014265	0.90	HRH3 (0.38)	HRH3HTTNPSR1PARP1KDM4E
	SCHEMBL1020102	0.90	PARP1 (0.37)	HRH3PARP1KDM4EALDH1A1HPGDS
	SCHEMBL1020298	0.89	HRH3 (0.49)	HRH3PARP1KDM4EALDH1A1HPGDS
	SCHEMBL1016676	0.89	HRH3 (0.38)	HRH3PARP1KDM4EALDH1A1KCNH2
	SCHEMBL1069967	0.87	PANK3 (0.41)	HRH3PARP1KDM4EALDH1A1
	SCHEMBL1016604	0.85	PARP1 (0.38)	HRH3HTTNPSR1PARP1KDM4E
	SCHEMBL1018081	0.84	HRH3 (0.39)	HRH3HTTNPSR1PARP1ALDH1A1
	SCHEMBL1018775	0.83	HRH3 (0.38)	HRH3HTTNPSR1PARP1KDM4E
	SCHEMBL1017178	0.82	HTT (0.38)	HRH3HTTNPSR1PARP1KDM4E
	SCHEMBL1017334	0.80	PDK2 (0.48)	HRH3HPGDSPLA2G7KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.