SCHEMBL1018081

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1016572	0.89	HRH3 (0.42)	HRH3MEN1KMT2AALDH1A1PDK2
	SCHEMBL1017334	0.89	PDK2 (0.48)	HRH3MEN1KMT2APDK2HPGDS
	SCHEMBL14420817	0.89	HPGDS (0.38)	HRH3MEN1KMT2APDK2HPGDS
	SCHEMBL1019845	0.86	HRH3 (0.45)	HRH3MEN1KMT2APDK2HPGDS
	SCHEMBL1015931	0.85	TLR4 (0.37)	HRH3MEN1KMT2AALDH1A1PDK2
	SCHEMBL1020634	0.85	HRH3 (0.38)	HRH3MEN1KMT2AALDH1A1PDK2
	SCHEMBL1017368	0.84	HRH3 (0.38)	HRH3ALDH1A1HPGDSHTTNPSR1
	SCHEMBL14420841	0.83	PARP1 (0.37)	HRH3MEN1KMT2AALDH1A1PDK2
	SCHEMBL1017186	0.83	HRH3 (0.37)	HRH3MEN1KMT2AALDH1A1HPGDS
	SCHEMBL1016469	0.82	HPGDS (0.58)	HRH3MEN1KMT2APDK2HPGDS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.