SCHEMBL1017451

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1019030	0.85	S1PR1 (0.41)	HRH3ALDH1A1PKMGAAHSD17B10
	SCHEMBL1016627	0.85	SCN9A (0.40)	HRH3ALDH1A1PKMGAAHSD17B10
	SCHEMBL1016990	0.84	HRH3 (0.43)	HRH3KCNH2
	SCHEMBL1018543	0.84	HRH3 (0.38)	HRH3ALDH1A1PKMGAAHSD17B10
	SCHEMBL12707530	0.83	ALDH1A1 (0.39)	HRH3ALDH1A1PKMGAAHSD17B10
	SCHEMBL1018075	0.83	HRH3 (0.49)	HRH3ALDH1A1PKMGAAHSD17B10
	SCHEMBL1017130	0.83	HRH3 (0.43)	HRH3ALDH1A1PKMGAAHSD17B10
	SCHEMBL1020154	0.83	MCHR1 (0.48)	HRH3ALDH1A1PKMGAAHSD17B10
	SCHEMBL1020898	0.82	HRH3 (0.42)	HRH3ALDH1A1KMT2ATSHRKCNH2
	SCHEMBL1016165	0.82	ALDH1A1 (0.40)	HRH3ALDH1A1PKMGAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.