⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12308399 | 0.75 | — | — | |
| SCHEMBL12177982 | 0.73 | — | — | |
| SCHEMBL19418761 | 0.68 | — | — | |
| SCHEMBL29720809 | 0.62 | — | — | |
| SCHEMBL11955237 | 0.62 | — | — | |
| SCHEMBL12945462 | 0.62 | — | — | |
| SCHEMBL9192722 | 0.62 | — | — | |
| SCHEMBL7260428 | 0.62 | — | — | |
| SCHEMBL5266114 | 0.60 | — | — | |
| SCHEMBL9921478 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008322-B | sulfonamide derivatives as BC L-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE 公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-105793239-A | UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF | 珊瑚防晒私人有限公司 | 2016-07-20 | — | — | CN | disclosed |
| WO-2012012478-A1 | ALDOSTERONE SYNTHASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-01-26 | — | — | WO | disclosed |