Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607369 | 0.86 | KDM4E (0.71) | KDM4EHSD17B10MAPTTP53KMT2A | |
| SCHEMBL2610178 | 0.86 | KDM4E (0.55) | KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL2607470 | 0.85 | KDM4E (0.69) | KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL2607350 | 0.85 | KDM4E (0.62) | KDM4EHSD17B10BCHEKMT2A | |
| SCHEMBL2610217 | 0.85 | KDM4E (0.62) | KDM4EHSD17B10KMT2A | |
| SCHEMBL2607451 | 0.83 | BCHE (0.52) | KDM4EBCHEMAPTTP53KMT2A | |
| SCHEMBL2610183 | 0.83 | MEN1 (0.77) | KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL2607598 | 0.82 | MEN1 (0.69) | KDM4EHSD17B10BCHEMAPTKMT2A | |
| SCHEMBL10175827 | 0.81 | KMT2A (0.70) | KDM4EMAPTKMT2A | |
| SCHEMBL15643320 | 0.81 | KCNH2 (0.58) | KDM4EHSD17B10BCHEPIN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101096-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Microbial Infections | University of Georgia Foundation, Inc. (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101096-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Microbial Infections | IMPDH1, IMPDH2, IMPA1 | KDM4E 1620/4885HSD17B10 542/4885BCHE 1002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.