SCHEMBL10176156

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12005974	0.93	HRH3 (0.62)	MEN1KMT2AKDM4EALDH1A1HRH3
	SCHEMBL14100107	0.88	KDM4E (0.64)	MEN1KMT2AKDM4EHRH3LTA4H
	SCHEMBL214568	0.88	MEN1 (0.57)	MEN1KMT2AKDM4EALDH1A1HRH3
	SCHEMBL23640213	0.86	MEN1 (0.58)	MEN1KMT2AKDM4EALDH1A1HRH3
	SCHEMBL2946059	0.86	NPC1 (0.71)	MEN1KMT2AKDM4EALDH1A1HRH3
	SCHEMBL6035058	0.85	MEN1 (0.55)	MEN1KMT2AKDM4EALDH1A1HRH3
	SCHEMBL10360467	0.83	HRH3 (0.50)	MEN1KMT2AKDM4EHRH3LTA4H
	SCHEMBL2204177	0.83	MEN1 (0.52)	MEN1KMT2AKDM4EALDH1A1HRH3
	SCHEMBL14419243	0.82	KDM4E (0.59)	MEN1KMT2AKDM4EALDH1A1HRH3
	SCHEMBL16815651	0.82	MEN1 (0.55)	MEN1KMT2AKDM4EALDH1A1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.