Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK3 | O43781 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | CDC7 | O00311 | 2/20 | 0.37 |
| ▸ | PLK4 | O00444 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | LYN | P07948 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | CLK2 | P49760 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL651021 | 1.00 | DYRK3 (0.41) | DYRK3MEN1KMT2APTP4A3CSNK2A1 | |
| SCHEMBL651666 | 1.00 | DYRK3 (0.41) | DYRK3MEN1KMT2APTP4A3CSNK2A1 | |
| SCHEMBL10176312 | 0.88 | PTPN7 (0.49) | DYRK3MEN1KMT2ACSNK2A1DAPK3 | |
| SCHEMBL10226351 | 0.88 | MET (0.44) | DYRK3MEN1KMT2ACSNK2A1EGFR | |
| SCHEMBL652615 | 0.88 | PTPN7 (0.49) | DYRK3MEN1KMT2ACSNK2A1DAPK3 | |
| SCHEMBL652616 | 0.88 | PTPN7 (0.49) | DYRK3MEN1KMT2ACSNK2A1DAPK3 | |
| SCHEMBL649011 | 0.88 | MET (0.44) | DYRK3MEN1KMT2ACSNK2A1EGFR | |
| SCHEMBL649012 | 0.88 | MET (0.44) | DYRK3MEN1KMT2ACSNK2A1EGFR | |
| SCHEMBL653261 | 0.86 | NPC1 (0.50) | DYRK3MEN1KMT2ACSNK2A1EGFR | |
| SCHEMBL653260 | 0.86 | NPC1 (0.50) | DYRK3MEN1KMT2ACSNK2A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119812-B2 | Thiazolidinone derivative | SBI BIOTECH CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-8119812-B2 | Thiazolidinone derivative | SBI BIOTECH CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| WO-2010122979-A1 | THIAZOLIDINONE DERIVATIVE | ＳＢＩバイオテック株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | CDC7, CDK17, CDCA2 | DYRK3 1808/4885MEN1 1406/4885KMT2A 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.