SCHEMBL10176834

SCHEMBL10176834

BCC(=O)C1(C(F)(F)F)CCC1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.38
RIPK1 Q13546 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10177484 0.78 DGAT1 (0.38) DGAT1RIPK1
SCHEMBL13096841 0.78 DGAT1 (0.38) DGAT1RIPK1
SCHEMBL23009522 0.76 DGAT1 (0.43) DGAT1RIPK1
SCHEMBL28799046 0.74 DGAT1 (0.44) DGAT1RIPK1
SCHEMBL1012654 0.74 DGAT1 (0.34) DGAT1RIPK1
SCHEMBL17586 0.72 DGAT1 (0.43) DGAT1RIPK1
SCHEMBL1515557 0.70 DGAT1 (0.46) DGAT1RIPK1
SCHEMBL1939082 0.70 DGAT1 (0.41) DGAT1RIPK1
SCHEMBL12928711 0.70 DGAT1 (0.41) DGAT1RIPK1
SCHEMBL23009397 0.69 DGAT1 (0.38) DGAT1RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012081736-A1 CONTINUOUS ARYCYCLIC COMPOUND MITSUBISHI TANABE PHARMA CORPORATION (JP) 2012-06-21 WO disclosed