⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12821068 | 1.00 | — | — | |
| SCHEMBL11892679 | 1.00 | — | — | |
| SCHEMBL8027929 | 0.83 | HTT (0.33) | — | |
| SCHEMBL9945810 | 0.80 | FDPS (0.33) | — | |
| SCHEMBL9946298 | 0.80 | FDPS (0.33) | — | |
| SCHEMBL18134873 | 0.77 | — | — | |
| SCHEMBL9944457 | 0.77 | — | — | |
| SCHEMBL10286000 | 0.75 | — | — | |
| SCHEMBL8619080 | 0.75 | — | — | |
| SCHEMBL12871330 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102942449-B | Synthetic method of 2,2-bis (trifluoroethyl) propanol | WUXI APPTEC CO LTD | 2015-01-07 | — | — | CN | claimed |
| CN-102942449-A | Synthetic method of 2,2-bis (trifluoroethyl) propanol | WUXI APPTEC CO LTD | 2013-02-27 | — | — | CN | claimed |
| US-8304403-B2 | Heterocyclic CETP inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-06 | — | — | US | claimed |
| WO-2023230542-A2 | PYRAZOLO[1,5-a]PYRIDINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023230543-A1 | INDOLIZINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023230540-A2 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| US-20230357254-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-09 | — | — | US | disclosed |
| US-20230337520-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-19 | — | — | US | disclosed |
| US-11702422-B2 | Imidazopyridazines as modulators of IL-17 | JANSSEN PHARMACEUTICA NV (BE) | 2023-07-18 | — | — | US | disclosed |
| EP-3750880-B1 | PYRAZINE-2(1H)-KETONE COMPOUND ACTING AS FGFR INHIBITOR | ZHANGZHOU PIEN TZE HUANG PHARM (CN) | 2022-12-21 | — | — | EP | disclosed |
| US-11286248-B2 | Pyrazine-2(1H)-ketone compound acting as FGFR inhibitor | ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD. (CN) | 2022-03-29 | — | — | US | disclosed |
| CN-102942449-A | Synthetic method of 2,2-bis (trifluoroethyl) propanol | WUXI APPTEC CO LTD | 2013-02-27 | — | — | CN | disclosed |
| CN-102942449-A | Synthetic method of 2,2-bis (trifluoroethyl) propanol | WUXI APPTEC CO LTD | 2013-02-27 | — | — | CN | disclosed |
| US-20120220767-A1 | AMINOTHIAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-08-30 | — | — | US | disclosed |
| WO-2012064269-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF Αβ-RELATED DISEASES | ASTRAZENECA AB (SE) | 2012-05-18 | — | — | WO | disclosed |
| WO-2011048936-A1 | AMINOTHIAZOLE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011037793-A1 | SUBSTITUTED AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OF DIABETES | MERCK SHARP & DOHME CORP. (US) | 2011-03-31 | — | — | WO | disclosed |
| US-4883806-A | ACARICIDES | ROUSSEL UCLAF (FR) | 1989-11-28 | — | — | US | disclosed |
| US-4732903-A | MITICIDES | ROUSSEL UCLAF (FR) | 1988-03-22 | — | — | US | disclosed |
| US-4542142-A | Insecticidal cyclopropane carboxylic acid derivatives with 3-unsaturated-side chain | ROUSSEL UCLAF (FR) | 1985-09-17 | — | — | US | disclosed |