Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9940345 | 0.87 | DGAT1 (0.79) | DGAT1 | |
| SCHEMBL9935600 | 0.83 | DGAT1 (0.49) | DGAT1 | |
| SCHEMBL9935598 | 0.81 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL15283166 | 0.80 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL10176519 | 0.79 | DGAT1 (0.62) | DGAT1 | |
| SCHEMBL9940381 | 0.75 | DGAT1 (0.70) | DGAT1 | |
| SCHEMBL9940406 | 0.75 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL9940532 | 0.74 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL15297160 | 0.73 | DGAT1 (0.58) | DGAT1 | |
| SCHEMBL16660754 | 0.73 | DGAT1 (0.51) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081736-A1 | CONTINUOUS ARYCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-06-21 | — | — | WO | disclosed |