Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10181280 | 0.90 | FGFR3 (0.49) | FGFR3KDR | |
| SCHEMBL10178625 | 0.89 | FGFR3 (0.52) | FGFR3KDR | |
| SCHEMBL10178211 | 0.89 | FGFR3 (0.52) | FGFR3KDR | |
| SCHEMBL15984935 | 0.87 | FGFR3 (0.52) | FGFR3KDR | |
| SCHEMBL10178936 | 0.87 | FGFR3 (0.55) | FGFR3KDR | |
| SCHEMBL10177416 | 0.87 | FGFR3 (0.51) | FGFR3KDR | |
| SCHEMBL15984920 | 0.86 | FGFR3 (0.52) | FGFR3KDR | |
| SCHEMBL15984924 | 0.85 | FGFR3 (0.62) | FGFR3KDR | |
| SCHEMBL15800120 | 0.84 | FGFR3 (0.55) | FGFR3KDR | |
| SCHEMBL10177433 | 0.84 | FGFR3 (0.50) | FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088266-A2 | SUBSTITUTED IMIDAZOPYRIDAZINES AND BENZIMIDAZOLES AS INHIBITORS OF FGFR3 | INCYTE CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |