SCHEMBL1017993

SCHEMBL1017993

Cc1cc(N)c2[nH]nnc2c1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
LMNA P02545 2/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
NUDT1 P36639 1/20 0.32
POLB P06746 2/20 0.31
CYP2C9 P11712 1/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14086777 0.79 DYRK1A (0.30)
SCHEMBL9228666 0.79 GRIN2D (0.36) ALDH1A1LMNAGAAKDM4EMAPT
SCHEMBL11456922 0.76 NR4A2 (0.38) ALDH1A1SMN1; SMN2TDP1TP53CYP3A4
SCHEMBL31667203 0.76 POLB (0.31) POLBCYP2C9
SCHEMBL10998306 0.76 AR (0.33) POLBCYP2C9
SCHEMBL24500838 0.76 XDH (0.36) ALDH1A1MAPTPOLBCYP2C9
SCHEMBL30843987 0.73 DHODH (0.35) LMNAKDM4ETDP1
SCHEMBL12180620 0.72 FABP6 (0.33) ALDH1A1TSHR
SCHEMBL14086955 0.72
SCHEMBL14086770 0.72 TSHR (0.35) ALDH1A1LMNAGAAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121858-B1 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT ARKEMA INC (US) 2013-10-16 EP disclosed
US-8450401-B2 Aqueous coating composition having reduced plate out ARKEMA INC. (US) 2013-05-28 US disclosed
US-8450402-B2 Method for reducing plate out of aqueous coating compositions ARKEMA INC. (US) 2013-05-28 US disclosed
EP-2121824-B8 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC (US) 2011-02-23 EP disclosed
EP-2121824-B1 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC (US) 2011-01-12 EP disclosed
US-20100324169-A1 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES, INC (US) 2010-12-23 US disclosed
US-20100319579-A1 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC. 2010-12-23 US disclosed
EP-2121858-A2 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES INC. (US) 2009-11-25 EP disclosed
EP-2121824-A2 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2009-11-25 EP disclosed
WO-2008100608-A2 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES, INC (US) 2008-08-21 WO disclosed
WO-2008100607-A2 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES, INC (US) 2008-08-21 WO disclosed