SCHEMBL1018029

SCHEMBL1018029

C=CC(=O)NC(C)(C)CCN(C)C

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 4/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 2/20 0.32
HTT P42858 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
OPRM1 P35372 2/20 0.30
DRD3 P35462 2/20 0.30
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11046865 0.98 MEN1 (0.48) MEN1KMT2AALDH1A1CYP3A4CYP2C9
SCHEMBL10714327 0.83 MEN1 (0.38) MEN1KMT2AALDH1A1CYP3A4CYP2C9
SCHEMBL7115011 0.83 MEN1 (0.44) MEN1KMT2AALDH1A1CYP3A4CYP2C9
SCHEMBL2796188 0.82 MEN1 (0.47) MEN1KMT2AALDH1A1CYP3A4CYP2C9
SCHEMBL2142738 0.81 ALDH1A1 (0.49) MEN1KMT2AALDH1A1CYP3A4CYP2C9
Trimethylammonium SCHEMBL28830079 0.80 MEN1 (0.48) MEN1KMT2AALDH1A1CYP3A4CYP2C9
Hydrochloric Acid SCHEMBL1482113 0.79 ALDH1A1 (0.47) MEN1KMT2AALDH1A1CYP3A4CYP2C9
SCHEMBL15448877 0.79 MEN1 (0.53) MEN1KMT2AALDH1A1CYP3A4CYP2C9
SCHEMBL4906709 0.79 KMT2A (0.53) MEN1KMT2AALDH1A1CYP3A4CYP2C9
SCHEMBL20467953 0.79 MEN1 (0.53) MEN1KMT2AALDH1A1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US claimed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP claimed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 WO claimed
US-9580591-B2 Use of hybrid copolymers as protective colloids for polymers WACKER CHEMIE AG (DE) 2017-02-28 US claimed
US-9522986-B2 Mineral construction material based on polyvinyl-alcohol-stabilized polymerisates WACKER CHEMIE AG (DE) 2016-12-20 US claimed
EP-2935142-B1 USE OF HYBRID COPOLYMERS AS PROTECTIVE COLLOIDS FOR POLYMERS WACKER CHEMIE AG (DE) 2016-10-12 EP claimed
CN-104870494-B The purposes of the stable polymerisate of polyvinyl alcohol in mineral construction thing material WACKER CHEMIE AG (DE) 2016-06-01 CN claimed
EP-2935357-B1 USE OF POLYVINYL-ALCOHOL-STABILISED POLYMERISATES IN MINERAL CONSTRUCTION MATERIALS WACKER CHEMIE AG (DE) 2016-05-11 EP claimed
US-20150315374-A1 USE OF HYBRID COPOLYMERS AS PROTECTIVE COLLOIDS FOR POLYMERS WACKER CHEMIE AG (DE) 2015-11-05 US claimed
WO-2000002937-A1 INTERPENETRATING POLYMER NETWORK HYDROPHILIC HYDROGELS FOR CONTACT LENS SUNSOFT CORPORATION (US) 2000-01-20 WO claimed
EP-0563047-A4 1994-02-09 EP claimed
EP-0430963-B1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS ISP INVESTMENTS INC (US) 1994-01-12 EP claimed
EP-0563047-A1 FLUORINE CONTAINING SOFT CONTACT LENS HYDROGELS SALAMONE, Joseph C. (US) 1993-10-06 EP claimed
WO-1992011300-A1 FLUORINE CONTAINING SOFT CONTACT LENS HYDROGELS SALAMONE JOSEPH C (US) 1992-07-09 WO claimed
EP-0430963-A4 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS 1991-11-21 EP claimed
EP-0430963-A1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS. GAF CHEMICALS CORP (US) 1991-06-12 EP claimed
WO-1990001920-A1 HYDROLYSIS RESISTANT VINYL LACTAM AMINO ACRYLAMIDE POLYMERS GAF CHEMICALS CORPORATION (US) 1990-03-08 WO claimed
US-4088499-A METHYLENE GROUP CONTAINING POLYMERS EASTMAN KODAK COMPANY (US) 1978-05-09 US claimed
US-4038176-A RECLAIMING WASTE OILS CALGON CORPORATION (US) 1977-07-26 US claimed