Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.73 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.53 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2242766 | 0.90 | PTGER4 (0.66) | PTGER4PTGER2LMNAMAPTL3MBTL1 | |
| SCHEMBL1153664 | 0.90 | PTGER4 (0.59) | PTGER4PTGER2LMNAMAPTL3MBTL1 | |
| SCHEMBL4013417 | 0.88 | PTGER4 (0.76) | PTGER4PTGER2LMNAMAPTL3MBTL1 | |
| SCHEMBL13770803 | 0.88 | PTGER4 (0.66) | PTGER4PTGER2LMNAMAPTL3MBTL1 | |
| SCHEMBL4456806 | 0.84 | PTGER4 (1.00) | PTGER4PTGER2LMNAL3MBTL1KMT2A | |
| SCHEMBL22319397 | 0.83 | PTGER4 (0.85) | PTGER4PTGER2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL4014358 | 0.82 | PTGER4 (0.67) | PTGER4PTGER2LMNAL3MBTL1MRGPRX4 | |
| SCHEMBL1154192 | 0.81 | DNMT3A (0.53) | PTGER4MRGPRX4PTGER1AKR1C3 | |
| SCHEMBL1154081 | 0.81 | AKR1C3 (0.52) | PTGER4PTGER2MRGPRX4KMT2APTGER1 | |
| SCHEMBL4014415 | 0.80 | PTGER4 (0.64) | PTGER4PTGER2LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215065-B1 | CCR10 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-07-11 | — | — | EP | disclosed |