SCHEMBL1154081

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1153664	0.91	PTGER4 (0.59)	AKR1C3DNMT3APTGER4MRGPRX4PTGER1
	SCHEMBL1154192	0.90	DNMT3A (0.53)	AKR1C3DNMT3APTGER4MRGPRX4PTGER1
	SCHEMBL10181047	0.89	AKR1C3 (0.51)	AKR1C3DNMT3APTGER4KMT2AHDAC1
	SCHEMBL10305303	0.89	AKR1C3 (0.52)	AKR1C3DNMT3APTGER4MRGPRX4PTGER1
	SCHEMBL1154137	0.89	AKR1C3 (0.59)	AKR1C3DNMT3AMRGPRX4PTGER1KMT2A
	SCHEMBL1153680	0.89	NR4A2 (0.52)	AKR1C3DNMT3AMRGPRX4PTGER1NR4A2
	SCHEMBL1153994	0.88	AKR1C3 (0.51)	AKR1C3DNMT3AMRGPRX4PTGER1KMT2A
	SCHEMBL1154383	0.88	DNMT3A (0.56)	AKR1C3DNMT3AMRGPRX4PTGER1HDAC1
	SCHEMBL1153860	0.87	MRGPRX4 (0.50)	AKR1C3DNMT3AMRGPRX4PTGER1KMT2A
	SCHEMBL1154527	0.86	AKR1C3 (0.57)	AKR1C3DNMT3APTGER4MRGPRX4PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.