Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3060756 | 0.99 | MEN1 (0.47) | MEN1KMT2AUSP2HPGDLMNA | |
| SCHEMBL3064146 | 0.90 | HPGD (0.51) | MEN1KMT2AUSP2HPGDLMNA | |
| Bromide SCHEMBL3062614 | 0.89 | STAT3 (0.46) | STAT3 | |
| Bromide SCHEMBL3067318 | 0.89 | MEN1 (0.51) | MEN1KMT2AUSP2HPGDLMNA | |
| SCHEMBL3065452 | 0.88 | HPGD (0.52) | MEN1KMT2AUSP2HPGDLMNA | |
| Hydrochloric Acid SCHEMBL3069882 | 0.88 | ALDH1A1 (0.47) | MEN1KMT2AUSP2HPGDLMNA | |
| SCHEMBL10180854 | 0.87 | MEN1 (0.49) | MEN1KMT2AUSP2HPGDLMNA | |
| SCHEMBL3051195 | 0.87 | USP2 (0.45) | MEN1KMT2AUSP2HPGDLMNA | |
| Bromide SCHEMBL3060750 | 0.86 | MEN1 (0.48) | MEN1KMT2AUSP2HPGDLMNA | |
| Hydrochloric Acid SCHEMBL3055581 | 0.86 | USP2 (0.45) | MEN1KMT2AUSP2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | disclosed |