SCHEMBL10180883

SCHEMBL10180883

O=C(Oc1cc(F)ccc1F)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.56
MAPT P10636 4/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
SERPINE1 P05121 1/20 0.50
SLC6A3 Q01959 1/20 0.50
ESR1 P03372 2/20 0.49
ESR2 Q92731 2/20 0.49
MEN1 O00255 2/20 0.49
HSD17B10 Q99714 2/20 0.49
JAK2 O60674 1/20 0.49
USP2 O75604 1/20 0.49
GAA P10253 1/20 0.49
ALOX15 P16050 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
SLC2A1 P11166 1/20 0.48
SLC2A4 P14672 1/20 0.48
LMNA P02545 2/20 0.45
METAP2 P50579 1/20 0.45
METAP1 P53582 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10181125 0.86 KMT2A (0.56) KMT2AMAPTSMN1; SMN2SERPINE1SLC6A3
SCHEMBL1323923 0.85 KMT2A (0.63) KMT2AMAPTSMN1; SMN2SERPINE1SLC6A3
SCHEMBL2060064 0.83 KMT2A (0.55) KMT2AMAPTSMN1; SMN2SLC6A3ESR1
SCHEMBL10180737 0.82 KMT2A (0.55) KMT2AMAPTSMN1; SMN2SERPINE1SLC6A3
SCHEMBL932180 0.82 KMT2A (0.54) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
SCHEMBL10180340 0.81 KMT2A (0.50) KMT2AMAPTSMN1; SMN2SERPINE1SLC6A3
SCHEMBL2838742 0.81 SLC2A1 (0.57) KMT2AMAPTSMN1; SMN2SERPINE1ESR1
SCHEMBL27528294 0.81 SERPINE1 (0.67) SERPINE1GAASLC2A1SLC2A4LMNA
SCHEMBL14222888 0.81 CYP4F2 (0.48) KMT2AMAPTSMN1; SMN2SERPINE1SLC6A3
SCHEMBL2060208 0.81 CYP4F2 (0.48) KMT2AMAPTSMN1; SMN2SERPINE1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104112870-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2014-10-22 CN disclosed
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed
CN-102484281-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2012-05-30 CN disclosed