SCHEMBL10180340

SCHEMBL10180340

O=C(Oc1cc(F)cc(F)c1F)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.50
MAPT P10636 4/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
SLC6A3 Q01959 1/20 0.45
SERPINE1 P05121 1/20 0.45
MEN1 O00255 4/20 0.44
JAK2 O60674 1/20 0.44
USP2 O75604 1/20 0.44
GAA P10253 1/20 0.44
ALOX15 P16050 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 2/20 0.44
SLC2A1 P11166 1/20 0.43
SLC2A4 P14672 1/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
LMNA P02545 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10180097 0.86 KMT2A (0.53) KMT2AMAPTSMN1; SMN2ESR1ESR2
SCHEMBL28686055 0.81 KMT2A (0.49) KMT2AMAPTSMN1; SMN2ESR1ESR2
SCHEMBL10181125 0.81 KMT2A (0.56) KMT2AMAPTSMN1; SMN2ESR1ESR2
SCHEMBL10180883 0.81 KMT2A (0.56) KMT2AMAPTSMN1; SMN2ESR1ESR2
SCHEMBL10181363 0.81 MAPT (0.47) KMT2AMAPTSMN1; SMN2ESR1ESR2
SCHEMBL27539798 0.80 SERPINE1 (0.57) MAPTSMN1; SMN2ESR1SERPINE1GAA
SCHEMBL10180669 0.79 KMT2A (0.58) KMT2AMAPTSMN1; SMN2ESR1ESR2
SCHEMBL10180737 0.77 KMT2A (0.55) KMT2AMAPTSMN1; SMN2ESR1ESR2
SCHEMBL10179781 0.77 KMT2A (0.55) KMT2AMAPTSMN1; SMN2ESR1ESR2
SCHEMBL10179685 0.77 KMT2A (0.56) KMT2AMAPTSMN1; SMN2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104112870-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2014-10-22 CN disclosed
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed