Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 8/20 | 0.51 |
| ▸ | FNTB | P49356 | 8/20 | 0.51 |
| ▸ | SQLE | Q14534 | 1/20 | 0.50 |
| ▸ | CBLB | Q13191 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12266823 | 1.00 | KDM4E (0.58) | KDM4EATMKMT2APOLBALDH1A1 | |
| SCHEMBL5856997 | 1.00 | KDM4E (0.58) | KDM4EATMKMT2APOLBALDH1A1 | |
| SCHEMBL2023438 | 1.00 | KDM4E (0.58) | KDM4EATMKMT2APOLBALDH1A1 | |
| SCHEMBL11578341 | 1.00 | KDM4E (0.58) | KDM4EATMKMT2APOLBALDH1A1 | |
| SCHEMBL115233 | 0.96 | KDM4E (0.62) | KDM4EATMKMT2APOLBALDH1A1 | |
| SCHEMBL17629195 | 0.96 | KDM4E (0.62) | KDM4EATMKMT2APOLBALDH1A1 | |
| SCHEMBL1154071 | 0.96 | KDM4E (0.62) | KDM4EATMKMT2APOLBALDH1A1 | |
| SCHEMBL30098641 | 0.88 | KDM4E (0.63) | KDM4EATMKMT2APOLBALDH1A1 | |
| SCHEMBL9440265 | 0.87 | KDM4E (0.60) | KDM4EATMKMT2APOLBALDH1A1 | |
| SCHEMBL9440253 | 0.87 | KDM4E (0.60) | KDM4EATMKMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037069-A2 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-03-22 | — | — | WO | disclosed |