Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 4/20 | 0.53 |
| ▸ | FNTB | P49356 | 4/20 | 0.53 |
| ▸ | SQLE | Q14534 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440265 | 1.00 | KDM4E (0.60) | KDM4EATMKMT2APOLBALOX15 | |
| SCHEMBL21753670 | 0.93 | KDM4E (0.56) | KDM4EATMKMT2APOLBALOX15 | |
| SCHEMBL30919999 | 0.87 | KDM4E (0.55) | KDM4EATMKMT2APOLBALOX15 | |
| SCHEMBL2023438 | 0.87 | KDM4E (0.58) | KDM4EATMKMT2APOLBALOX15 | |
| SCHEMBL11578341 | 0.87 | KDM4E (0.58) | KDM4EATMKMT2APOLBALOX15 | |
| SCHEMBL12266823 | 0.87 | KDM4E (0.58) | KDM4EATMKMT2APOLBALOX15 | |
| SCHEMBL5856997 | 0.87 | KDM4E (0.58) | KDM4EATMKMT2APOLBALOX15 | |
| SCHEMBL10181090 | 0.87 | KDM4E (0.58) | KDM4EATMKMT2APOLBALOX15 | |
| SCHEMBL29578463 | 0.84 | KDM4E (0.64) | KDM4EATMKMT2APOLBALOX15 | |
| SCHEMBL10297988 | 0.84 | KDM4E (0.55) | KDM4EATMKMT2APOLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332143-B1 | 11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-[(E,E)-3,7,11-trimethyl-2,6,10-dodecatrienoate] | KURARAY CO (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5278156-A | Steroids | KURARAY CO., LTD. (JP) | 1994-01-11 | — | — | US | disclosed |
| US-5015746-A | Esterification of prednisolone with 3,7,11-trimethyl-2,6,10-dodecatrienoic acid in the presence of disubstituted aminopyridines and a condensing agents | KURARAY CO., LTD. (JP) | 1991-05-14 | — | — | US | disclosed |
| EP-0332143-A1 | 11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-[(E,E)-3,7,11-trimethyl-2,6,10-dodecatrienoate] | KURARAY CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |