SCHEMBL1018137

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1015267	0.90	KDM4E (0.43)	HRH3HTTNPSR1PARP1KMT2A
	SCHEMBL1017168	0.90	ALDH1A1 (0.46)	HRH3KMT2AALDH1A1KDM4EMAPT
	SCHEMBL1015720	0.89	KDM4E (0.41)	HRH3HTTPARP1KMT2AENPP2
	SCHEMBL1014671	0.88	HRH3 (0.43)	HRH3
	SCHEMBL1017884	0.87	KDM4E (0.43)	HRH3HTTNPSR1PARP1KMT2A
	SCHEMBL1017730	0.85	CFTR (0.40)	HRH3HTTNPSR1PARP1KMT2A
	SCHEMBL1016801	0.82	—	—
	SCHEMBL1017882	0.81	HSP90AA1 (0.45)	HRH3HTTNPSR1PARP1ENPP2
	SCHEMBL1020974	0.81	HSP90AA1 (0.44)	HRH3PARP1KMT2AALDH1A1KDM4E
	SCHEMBL1013876	0.81	PARP1 (0.36)	HRH3HTTNPSR1PARP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.