SCHEMBL1018152

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1018080	0.98	MCHR1 (0.52)	MCHR1KMT2AALPLALPIALPG
	SCHEMBL1017741	0.97	MCHR1 (0.51)	MCHR1KMT2AALPLALPIALPG
	SCHEMBL1018607	0.92	MCHR1 (0.45)	MCHR1HRH3
	SCHEMBL1019922	0.91	HRH3 (0.49)	MCHR1ALDH1A1HRH3GAAPKM
	SCHEMBL1016153	0.90	ALDH1A1 (0.48)	MCHR1KMT2AALDH1A1KDM4EHRH3
	SCHEMBL1016088	0.89	HRH3 (0.50)	MCHR1ALDH1A1KDM4EHRH3GAA
	SCHEMBL1020154	0.89	MCHR1 (0.48)	MCHR1ALDH1A1KDM2BHRH3GAA
	SCHEMBL1017606	0.89	NPSR1 (0.45)	MCHR1KMT2AALDH1A1KDM4EKDM2B
	SCHEMBL1014075	0.88	HRH3 (0.50)	MCHR1ALDH1A1L3MBTL1KDM4EHRH3
	SCHEMBL1016579	0.88	HRH3 (0.44)	MCHR1KMT2AALDH1A1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.