Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015644 | 1.00 | HTR6 (0.48) | HTR6PTGDR2HTR2CHTR2B | |
| SCHEMBL1015228 | 0.91 | HTR6 (0.48) | HTR6HTR2CHTR2B | |
| SCHEMBL1015227 | 0.91 | HTR6 (0.48) | HTR6HTR2CHTR2B | |
| SCHEMBL1013417 | 0.90 | HTR6 (0.47) | HTR6HTR2CHTR2B | |
| SCHEMBL1013418 | 0.90 | HTR6 (0.47) | HTR6HTR2CHTR2B | |
| SCHEMBL1015429 | 0.89 | HTR6 (0.47) | HTR6HTR2CHTR2B | |
| SCHEMBL1016305 | 0.87 | HTR6 (0.49) | HTR6HTR2CHTR2B | |
| SCHEMBL1012439 | 0.87 | HTR6 (0.49) | HTR6HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL1015772 | 0.86 | HTR6 (0.51) | HTR6HTR2CHTR2B | |
| SCHEMBL1013416 | 0.84 | HTR6 (0.47) | HTR6HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081890-B1 | ARYLSULFONYL PYRROLIDINES AS 5-HT6 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-01-12 | — | — | EP | claimed |