Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.55 |
| ▸ | PPARG | P37231 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186221 | 0.89 | PPARA (0.53) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL10184560 | 0.84 | PPARA (0.53) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL10184533 | 0.78 | PPARA (0.55) | PPARAPPARGCYP2C9KCNH2 | |
| SCHEMBL6513163 | 0.77 | PPARA (0.58) | PPARAPPARGTSHRUSP2CYP2C9 | |
| SCHEMBL5441860 | 0.75 | PPARA (0.56) | PPARAPPARG | |
| SCHEMBL5423717 | 0.75 | PPARA (0.58) | PPARAPPARGTSHRUSP2CYP2C9 | |
| SCHEMBL5437303 | 0.75 | PPARA (0.54) | PPARAPPARG | |
| SCHEMBL5423669 | 0.74 | PPARA (0.54) | PPARAPPARGMAPTMAPK1 | |
| SCHEMBL5434312 | 0.74 | PPARA (0.56) | PPARAPPARGCYP2C9KCNH2FFAR1 | |
| SCHEMBL5428115 | 0.74 | PPARA (0.56) | PPARAPPARGTSHRCYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531810-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD | BRISTOL MYERS SQUIBB CO (US) | 2012-02-01 | — | — | EP | disclosed |